ChemicalBook--->CAS DataBase List--->482-68-8

482-68-8

482-68-8 Structure

482-68-8 Structure
IdentificationBack Directory
[Name]

SARPAGINE
[CAS]

482-68-8
[Synonyms]

Raupin
Raupine
SARPAGINE
sarpagan-10,17-diol
Sarpagane-10,17-diol
[EINECS(EC#)]

207-583-2
[Molecular Formula]

C19H22N2O2
[MDL Number]

MFCD29078461
[MOL File]

482-68-8.mol
[Molecular Weight]

310.39
Chemical PropertiesBack Directory
[Melting point ]

320°C
[alpha ]

D20 +54° (c = 0.5 in pyridine)
[Boiling point ]

450.55°C (rough estimate)
[density ]

1.1396 (rough estimate)
[refractive index ]

1.5600 (estimate)
[pka]

10.24±0.40(Predicted)
Safety DataBack Directory
[RIDADR ]

1544
[HazardClass ]

6.1(b)
[PackingGroup ]

III
Hazard InformationBack Directory
[Description]

This base has been isolated from Rauwolfia serpentina and is an isomer of Ajmalinine (q.v.). Pharmacologically it has between three and four times the effect of the total Rauwolfia alkaloids on isolated rabbit uterus and is very specific. In the cat, the blood pres~ure is lowered by 0.5-2.0 mgm per kilo body weight. The toxicity is low.
[Definition]

ChEBI: An indole alkaloid that is sarpagan bearing hydroxy groups at positions 10 and 17.
[References]

Bodendorf, Eder., Naturwis<., 40, 342 (1953)
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