| Identification | Back Directory | [Name]
ANTIBIOTIC TPU-0037-C | [CAS]
485815-61-0 | [Synonyms]
TPU-0037C
ANTIBIOTIC TPU-0037-C
8-Dehydroxy-30-deMethyllydicaMycin
1-Pyrrolidinecarboximidamide, 2-[21-[1-[(2,5-dihydro-4-hydroxy-2-oxo-1H-pyrrol-3-yl)carbonyl]-1,2,4a,5,6,7,8,8a-octahydro-5-hydroxy-1,3-dimethyl-2-naphthalenyl]-2,6,10,14,18-pentahydroxy-11,17,19-trimethyl-4,8,12,16-heneicosatetraen-1-yl]-, (+)- | [Molecular Formula]
C46H72N4O9 | [MDL Number]
MFCD09954095 | [MOL File]
485815-61-0.mol | [Molecular Weight]
825.09 |
| Hazard Information | Back Directory | [Description]
TPU-0037C is a metabolite of the marine actinomycete S. platensis that is structurally similar to lydicamycin . It is active against Gram-positive bacteria (MICs = 0.39-3.13 μg/ml), including methicillin-resistant S. aureus strains (MIC = 3.13 μg/ml), but is ineffective against Gram-negative bacteria (MICs = >50 μg/ml). | [Uses]
Antibiotic TPU-0037-C is an agent with activity against gram-positive bacteria. | [Uses]
TPU-0037C, a close structural analogue of lydicamycin, has been shown to be highly active against MRSA. TPU-0037C is also closely related to BN 4515N which was isolated from a strain of Microtetraspora as a neuritogenic agent. |
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| Company Name: |
Lynnchem
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86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
| Company Name: |
Novachemistry
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44-20819178-90 02081917890 |
| Website: |
https://www.novachemistry.com/ |
| Company Name: |
Energy Chemical
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021-58432009 400-005-6266 |
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http://www.energy-chemical.com |
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