| Identification | Back Directory | [Name]
PORPHOBILINOGEN | [CAS]
487-90-1 | [Synonyms]
PBG
PORPHOBILINOGEN
porphobilinogen (synth.)
5-(Aminomethyl)-4-(carboxymethyl)pyrrole-3-propionic acid
5-(aminomethyl)-4-(carboxymethyl)-1h-pyrrole-3-propanoicaci
5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid
5-[AMINOMETHYL]-4-[CARBOXYMETHYL]-1H-PYRROLE-3-PROPANOIC ACID
1H-Pyrrole-3-propanoic acid, 5-(aminomethyl)-4-(carboxymethyl)-
3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid
3-[5-(aminomethyl)-4-(carboxymethyl)-1H-pyrrol-3-yl]propionic acid | [EINECS(EC#)]
207-666-3 | [Molecular Formula]
C10H14N2O4 | [MDL Number]
MFCD00005224 | [MOL File]
487-90-1.mol | [Molecular Weight]
226.23 |
| Chemical Properties | Back Directory | [Melting point ]
174-177℃ | [Boiling point ]
479℃ | [density ]
1.421 | [Fp ]
243℃ | [storage temp. ]
-20°C | [solubility ]
Aqueous Base (Slightly), Acetonitrile (Slightly), DMSO (Slightly) | [form ]
powder
| [pka]
4.22±0.10(Predicted) | [color ]
light yellow to pink
| [Merck ]
13,7681 | [BRN ]
220051 | [EPA Substance Registry System]
Porphobilinogen (487-90-1) |
| Hazard Information | Back Directory | [Uses]
An intermediate in the biosynthesis of Heme, found in the urine of patients with acute porphyria. | [Definition]
ChEBI: Porphobilinogen is a dicarboxylic acid that is pyrole bearing aminomethyl, carboxymethyl and 2-carboxyethyl substituents at positions 2, 3 and 4 respectively. It has a role as a metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a member of pyrroles, a dicarboxylic acid and an aralkylamino compound. It is a conjugate acid of a porphobilinogen(1-). | [Biochem/physiol Actions]
Intermediate in the biosynthesis of heme. | [Purification Methods]
Porphobilinogen recrystallises as the monohydrate (pink crystals) from dilute NH4 OAc solutions of pH 4, and is dried in vacuo. The hydrochloride monohydrate has m 165-170o(dec) (from dilute HCl). [Jackson & MacDonald Can J Chem 35 715 1957, Westall Nature 170 614 1952, Bogarad J Am Chem Soc 75 3610 1953, Beilstein 22/14 V 210.] |
|
| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|