| Identification | Back Directory | [Name]
GOSSYPETIN | [CAS]
489-35-0 | [Synonyms]
C.I.75750
Equisporol
GOSSYPETIN
Articulatidin
GOSSYPETIN(RG)
8-Hydroxyquercetin
GOSSYPETIN WITH HPLC
3,3',4',5,7,8-Hexahydroxyflavone
3,5,7,8,3',4'-HEXAHYDROXYFLAVONE
3,5,7,3',4',8-HEXAHYDROXYFLAVONE
3,5,7,8,3',4'-Hexahydroxyflavone
2-(3,4-Dihydroxyphenyl)-3,5,7,8-tetrahydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7,8-tetrahydroxy- | [Molecular Formula]
C15H10O8 | [MDL Number]
MFCD00017680 | [MOL File]
489-35-0.mol | [Molecular Weight]
318.24 |
| Chemical Properties | Back Directory | [Melting point ]
302-304°C | [Boiling point ]
679.3±55.0 °C(Predicted) | [density ]
1.912 | [storage temp. ]
Hygroscopic, Refrigerator, under inert atmosphere | [solubility ]
DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)) | [form ]
Solid | [pka]
6.47±0.40(Predicted) | [color ]
Dark Yellow | [LogP]
1.160 (est) |
| Hazard Information | Back Directory | [Uses]
3,5,7,8,3'',4''-Hexahydroxyflavone is a flavonoid found in H. sabdariffa and has diverse biological activities/properties. 3,5,7,8,3'',4''-Hexahydroxyflavone is the anxiolytic and antidepressant constituents of H. sabdariffa calyces. | [Definition]
ChEBI: Gossypetin is a hexahydroxyflavone having the hydroxy groups placed at the 3-, 3'-, 4'-, 5- 7- and 8-positions. It has a role as a plant metabolite. It is a 7-hydroxyflavonol and a hexahydroxyflavone. It is a conjugate acid of a gossypetin-3-olate and a gossypetin(1-). | [Biological Activity]
Gossypetin is a hexahydroxylated flavonoid found in the flowers and the calyx of Hibiscuswhich exhibits numerous pharmacological effectsincluding antioxidantantibacterial and anticancer activities. It induces apoptosis and autophagic cell death in prostate cancer cells. Gossypetin is a potent inhibitor of MKK3 and MKK6 protein kinases th at suppresses esophageal cancer growth. | [storage]
Store at -20°C |
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