| Identification | Back Directory | [Name]
Eliglustat | [CAS]
491833-29-5 | [Synonyms]
CS-1540
Eliglustat
Genz 99067
Elli Gustast
Eliglustat(Genz-99067)
Eliglustat(GENZ 112638)
GENZ-99067; GENZ99067; GENZ 99067
GENZ-99067;GENZ99067;GENZ 99067;ELIGLUSTAT TARTRATE;GENZ-112638
N-[(1r,2r)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-pyrrolidin-1-ylpropan-2-yl]octanamide
N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-
pyrrolidinyl)-2-propanyl]octanamide
N-[(1R,2R)-2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]-octanamide
Octanamide, N-[(1R,2R)-2-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-hydroxy-1-(1-pyrrolidinylmethyl)ethyl]- | [Molecular Formula]
C23H36N2O4 | [MDL Number]
MFCD19443735 | [MOL File]
491833-29-5.mol | [Molecular Weight]
404.54 |
| Chemical Properties | Back Directory | [Melting point ]
87-92°C | [Boiling point ]
615.5±55.0 °C(Predicted) | [density ]
1.123±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,2-8°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
13.45±0.20(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Uses]
Eliglustat is a specific and potent inhibitor of glucosylceramide synthase. | [Definition]
ChEBI: A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltr
nsferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease. |
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