| Identification | Back Directory | [Name]
ISOMITRAPHYLLINE | [CAS]
4963-01-3 | [Synonyms]
ISOMITRAPHYLLINE
7-Isomitraphylline
AJMALICIN OXINDOLE A
ISOMITRAPHYLLINE(SH)
Ajmalicine oxindole A
(7S)-19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3S,4'aS,5'aS,10'aR)- | [Molecular Formula]
C21H24N2O4 | [MDL Number]
MFCD03788776 | [MOL File]
4963-01-3.mol | [Molecular Weight]
368.43 |
| Hazard Information | Back Directory | [Description]
This Mitragyna alkaloid has been isolated from the leaves of M. speciosa Korth
by Beckett and his colleagues. It is an amorphous solid which cannot be obtained
crystalline. The base may be characterized as the picrate which forms pale yellow
needles from MeOH, m.p. 223°C (dec.). A methylgroup, a methoxycarbonyl
group and one imino group are present. The second nitrogen atom is tertiary. | [Uses]
Isomitraphylline is an oxoindole alkaloid derivied from amazonian plants and maintain medicinal benefits. Used in the treatment of ulcers, arthritis, etc. | [References]
Beckett et al., J. Pharm. Pharmacol., 17,753 (1965)
Beckett et ai., Planta Med., 14, 266 (1966)
Structure:
Finch, Taylor., J. Amer. Chem. Soc., 84,3871 (1962)
Prepara tion:
Seaton et al., Can. J. Chem., 38, 1035 (1960) |
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