| Identification | Back Directory | [Name]
2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)- (9CI) | [CAS]
496926-08-0 | [Synonyms]
Massarigenin C
2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)-
2-Oxaspiro[4.5]dec-8-ene-1,7-dione, 4,6-dihydroxy-10-methyl-3-methylene-, (4R,5R,6R,10R)-rel-(-)- (9CI) | [Molecular Formula]
C11H12O5 | [MOL File]
496926-08-0.mol | [Molecular Weight]
224.21 |
| Hazard Information | Back Directory | [Description]
Massarigenin C is a fungal metabolite that has been found in M. flavorosea and has enzyme inhibitory activities. Massarigenin C inhibits neuraminidase in vitro (IC50 = 4.15 μM). It is also an inhibitor of yeast α-glucosidase (IC50 = 1.25 mM). It reduces the postprandial peak in blood glucose levels in an oral sucrose tolerance test in normo- and hyperglycemic mice when administered at doses of 3.2, 10, and 31.6 mg/kg. |
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