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49710-99-8

49710-99-8 Structure

49710-99-8 Structure
IdentificationBack Directory
[Name]

2'-hydroxy-5'-methoxypropiophenone
[CAS]

49710-99-8
[Synonyms]

Methoxamine Impurity 18
Methoxamine Impurity 7 HCl
2'-hydroxy-5'-methoxypropiophenone
1-(2-Hydroxy-5-methoxyphenyl)-1-propanone
[EINECS(EC#)]

256-440-0
[Molecular Formula]

C10H12O3
[MDL Number]

MFCD00598386
[MOL File]

49710-99-8.mol
[Molecular Weight]

180.2
Chemical PropertiesBack Directory
[Melting point ]

47–49°C
[storage temp. ]

Refrigerator
[solubility ]

Chloroform (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Pale Yellow
Hazard InformationBack Directory
[Uses]

1-(2-Hydroxy-5-methoxyphenyl)-1-propanone can be used as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators.
[Preparation]

Preparation by Fries rearrangement of p-methoxyphenyl propionate,
with titanium tetrachloride without solvent at 120° for 1 h (74%)
with aluminium chloride in nitrobenzene at 80–100° for 2 h (41%).
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