| Identification | Back Directory | [Name]
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester | [CAS]
503614-91-3 | [Synonyms]
TECO-008
Apixaban-3
Apixaban V
BMS-589154)
BMS-589154)）
Apixaban N-1
BMS-589149-01
Apixaban INT 02
ApixabanIm purit
Apixaban Ethyl Ester
Apixaban Impurity BZ
Apixaba inretMediate C
Apixaban Ester Impurity
Impurity of apixaban381
Apixaban Ethyl Ester Imp
Apixaban Impurity C
ethyl
Ethyl 1-(4-methoxyphenyl)
Apixaban Ethyl ester Impurity
Apixaban Intermediate 4,5,6,7
-7-oxo-6-(4-(2-oxopiperidin-1-yl)
Apixaban Impurity 9 (BMS-589149-01)
4-c]pyridine-3-carboxylic acid ethyl ester
-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4
ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazo
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyr
ethyl 1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate
1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
Ethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1yl)phenyl)-4,5,6,7-tetrahydro-1H- pyrozolo[3,4-c] pyridine-3-carboxylate
1H-Pyrazolo[3,4-c]pyridine-3-carboxylicacid,4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-,ethylester
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
4,5,6,7-Tetrahydro-1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1h-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester
1-(4-Methoxyphenyl)-7-oxo -6-[4-(2-oxopiperidin-1-yl) phenyl]-4,5,6,7-tetrahydro- 1H-pyrazolo[3,4-c]pyridine -3-carboxylic acid ethyl este
Apixaban ethyl ester impuity
Ethyl 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-
yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3- carboxylate
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl 1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid e | [EINECS(EC#)]
700-890-7 | [Molecular Formula]
C27H28N4O5 | [MDL Number]
MFCD18072444 | [MOL File]
503614-91-3.mol | [Molecular Weight]
488.535 |
| Chemical Properties | Back Directory | [Melting point ]
175 - 180°C | [Boiling point ]
758.7±60.0 °C(Predicted) | [density ]
1.34 | [vapor pressure ]
0.001Pa at 25℃ | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
0.78±0.20(Predicted) | [color ]
White to Pale Beige | [InChI]
InChI=1S/C27H28N4O5/c1-3-36-27(34)24-22-15-17-30(19-9-7-18(8-10-19)29-16-5-4-6-23(29)32)26(33)25(22)31(28-24)20-11-13-21(35-2)14-12-20/h7-14H,3-6,15-17H2,1-2H3 | [InChIKey]
PULNLYVCJSOXKS-UHFFFAOYSA-N | [SMILES]
C1(=O)N(C2=CC=C(N3CCCCC3=O)C=C2)CCC2C(C(OCC)=O)=NN(C3=CC=C(OC)C=C3)C1=2 | [LogP]
172 at 22.8℃ |
| Hazard Information | Back Directory | [Uses]
Apixaban V is a derivative of Apixaban (A726700), a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation |
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