| Identification | Back Directory | [Name]
Columbianadin | [CAS]
5058-13-9 | [Synonyms]
ZosiMin
ColuMbianin
Columbianadin
Columbianetin angelate
Columbianadin 5058-13-9
Columbianadin Columbianadin
Columbianadin, 98%, from Angelica pubescens Maxim.f. biserrata Shan et Yuan
2-[(8S)-2-oxo-8,9-dihydrofuro[2,3-h]chromen-8-yl]propan-2-yl (Z)-2-methylbut-2-enoate
(S)-2-(2-oxo-8,9-dihydro-2H-furo[2,3-h]chromen-8-yl)propan-2-yl (Z)-2-methylbut-2-enoate
(Z)-2-Methylbut-2-enoic Acid (S)-2-(2-Oxo-8,9-dihydro-2H-furo[2,3-h]chromen-8-yl)propan-2-yl Ester
(S)-8-[1-[(Z)-2-Methyl-2-butenoyloxy]-1-methylethyl]-8,9-dihydro-2H-furo[2,3-h]-1-benzopyran-2-one
2-Butenoic acid, 2-methyl-, 1-[(8S)-8,9-dihydro-2-oxo-2H-furo[2,3-h]-1-benzopyran-8-yl]-1-methylethyl ester, (2Z)- | [Molecular Formula]
C19H20O5 | [MDL Number]
MFCD07781426 | [MOL File]
5058-13-9.mol | [Molecular Weight]
328.36 |
| Chemical Properties | Back Directory | [Melting point ]
117.0 to 121.0 °C | [Boiling point ]
482.3±45.0 °C(Predicted) | [density ]
1.232±0.06 g/cm3(Predicted) | [solubility ]
DMSO : 33.33 mg/mL (101.50 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble) | [form ]
powder to crystal | [color ]
White to Almost white |
| Hazard Information | Back Directory | [Uses]
Columbianedin, a coumarin compounds, is one of the main bioactive constituents of Angelica pubescens Maxim f. biserrata Shan et Yuan and is studied for its antiinflammatory and analgesic properties. Potential anti-tumor agent. Cytotoxic. | [Definition]
ChEBI: Columbianadin is an alpha,beta-unsaturated carboxylic ester obtained by formal condensation of the carboxy group of angelic acid with the hydroxy group of 2-[(8S)-2-oxo-8,9-dihydro-2H-furo[2,3-h][1]benzopyran-8-yl]propan-2-ol. It has a role as an anti-inflammatory agent, an apoptosis inducer, a hepatoprotective agent, an antineoplastic agent, a rat metabolite and a plant metabolite. It is a furanocoumarin and an alpha,beta-unsaturated carboxylic ester. It is functionally related to an angelic acid. |
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