| Identification | Back Directory | [Name]
8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT | [CAS]
510774-50-2 | [Synonyms]
8-CPT-2'-O-ME CAMP NA
CAMP, 8-CPT-2'-O-ME, NA
-O-methyladenosine3&rsquo
8CPT-2ME-CAMP, SODIUM SALT
8-(4-Chlorophenylthio)-2&rsquo
-cyclicMonophosphateSodiumSalt
8-PCPT-2''-O-ME-CAMP SODIUM SALT
8-[(4-Chlorophenyl)thio]-2'-O-methyladenosine cyclic 3',5'-(hydrogen phosphate)
8-(4-CHLOROPHENYLTHIO)-2',O-METHYLADENOSINE 3',5'-CYCLIC MONOPHOSPHATE SODIUM SALT
Adenosine, 8-[(4-chlorophenyl)thio]-2'-O-methyl-, cyclic 3',5'-(hydrogen phosphate)
ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-(4-CHLOROPHENYLTHIO)-2'-O-METHYL-, SODIUM SALT | [Molecular Formula]
C17H17ClN5O6PS | [MDL Number]
MFCD04974491 | [MOL File]
510774-50-2.mol | [Molecular Weight]
485.84 |
| Hazard Information | Back Directory | [Uses]
8-(4-Chlorophenylthio)-2''-O-methyladenosine 3'',5''-cyclic Monophosphate sodium salt is an activator of the Epac cAMP receptor. It can be used in biological study of interaction between TCL1 and Epac1 in activation of Akt kinases in plasma membranes and nuclei of 8-CPT-2-O-Me-cAMP-stimulated macrophages | [Biological Activity]
Selective activator of Epac, the cAMP-sensitive guanine nucleotide-exchange factor for Rap1 and Rap2. Activates Epac1 (EC 50 = 2.2 mM), but not PKA (EC 50 > 10 mM). Stimulates Epac-mediated Ca 2+ -mediated Ca 2+ release in pancreatic b-cells in vitro . |
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Energy Chemical
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Alexis Corporation
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