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514-68-1

514-68-1 Structure

514-68-1 Structure
IdentificationBack Directory
[Name]

estriol succinate
[CAS]

514-68-1
[Synonyms]

Einecs 208-185-1
Estrioli succinas
estriol succinate
Estriolo succinato
Oestriol succinate
Oestrioli succinas
Estriolo succinato [dcit]
Estrioli succinas [inn-latin]
113-22-4 (Di-hydrochloride salt)
Estriol 16,17-bis(sodium hemisuccinate)
Estra-1,3,5(10)-triene-3,16α,17β-triol 16,17-bis(hydrogen succinate)
Estra-1,3,5(10)-triene-3,16,17-triol, 16,17-bis(4-hydrogen butanedioate), (16α,17β)-
[EINECS(EC#)]

208-185-1
[Molecular Formula]

C26H32O9
[MDL Number]

MFCD22493350
[MOL File]

514-68-1.mol
[Molecular Weight]

488.53
Chemical PropertiesBack Directory
[Boiling point ]

716.8±60.0 °C(Predicted)
[density ]

1.38±0.1 g/cm3(Predicted)
[pka]

4.40±0.17(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS08,GHS07
[Signal word ]

Warning
[Hazard statements ]

H332-H302-H351-H361-H312
[Precautionary statements ]

P201-P202-P281-P308+P313-P405-P501-P261-P271-P304+P340-P312-P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P201-P202-P281-P308+P313-P405-P501
Hazard InformationBack Directory
[Originator]

Hemostyptanon,Endopancrine,France,1966
[Uses]

Estrogen.
[Definition]

ChEBI: Estriol succinate is a steroid ester and a hemisuccinate.
[Manufacturing Process]

Succinic anhydride and 60 ml of pyridine is heated at 90°C for 4 hours, after which the reaction mixture is poured into water. The aqueous solution is extracted with ether, the ether layer is separated, washed with diluted sulfuric acid and after that with water until neutral, then evaporated to dryness to obtain 14 grams of an amorphous substance. Melting point 82° to 86°C. This drying residue proves to consist of a mixture of estriol disuccinate and estriol monosuccinate, which are separated by repeated crystallization from a mixture of methanol and water.
[Brand name]

Theelol (Parke-Davis).
[Therapeutic Function]

Estrogen
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