| Identification | Back Directory | [Name]
N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine | [CAS]
519178-28-0 | [Synonyms]
TNP
IP3K Inhibitor
IP6K Inhibitor
TNP >=95% (HPLC)
IP6K1 inhibitor TNP
(TNP)
IP6K Inhibitor - CAS 519178-28-0 - Calbiochem
N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl)purine
N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-1H-Purine-2,6-diamine
N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]-9H-Purine-2,6-diamine
9H-Purine-2,6-diamine, N6-[(4-nitrophenyl)methyl]-N2-[[3-(trifluoromethyl)phenyl]methyl]- | [EINECS(EC#)]
247-759-6 | [Molecular Formula]
C20H16F3N7O2 | [MDL Number]
MFCD16875436 | [MOL File]
519178-28-0.mol | [Molecular Weight]
443.38 |
| Chemical Properties | Back Directory | [Boiling point ]
723.4±70.0 °C(Predicted) | [density ]
1.543±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
DMSO: ≥10mg/mL | [form ]
Yellow solid | [pka]
10.51±0.10(Predicted) | [color ]
yellow |
| Hazard Information | Back Directory | [Uses]
TNP provides a means of selectively and rapidly modulating cellular InsP7 levels in vivo without affecting levels of other inositol phosphates. | [Biochem/physiol Actions]
TNP is a potent and selective IP6K inhibitor; less selective inhibitor of IP3K. Discovery of TNP as an inositol trisphosphate (IP3) kinase inhibitor was first reported in 2002, However, a recent reference shows that TNP is more potent as an IP6K inhibitor, making it valuable for study of inositol pyrophosphates. | [storage]
Store at +4°C |
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