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52050-17-6

52050-17-6 Structure

52050-17-6 Structure
IdentificationBack Directory
[Name]

GLUCOPSYCHOSINE
[CAS]

52050-17-6
[Synonyms]

sphingosylbeta-glucoside
Glucosyl-C18-sphingosine
1-β-D-Glucosylsphingosine
1-β-D-Glucosylsphingosine
Glucosylsphingosine, plant
GLUCOSYL(Β) SPHINGOSINE (D18:1)
1--D-Glucosylsphingosine (d18:1)
1-β-D-Glucosylsphingosine (d18:1)
D-glucosyl-1-1'-D-erythro-sphingosine
1-β-D-Glucosylsphingosine (d18:1) (buttermilk)
2-AMino-3-hydroxy-4-octadecenyl β-D-Glucopyranoside
(2S,3R,4E)-2-AMino-3-hydroxy-4-octadecenyl β-D-Glucopyranoside
β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl
beta-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl
2-(2-amino-3-hydroxy-octadec-4-enoxy)-6-(hydroxymethyl)oxane-3,4,5-triol
b-D-Glucopyranosyl-1,1’-2’-amino-4’-octadecene-1’,3’-diol Synonym:Glucosylsphingosine
[Molecular Formula]

C24H47NO7
[MDL Number]

MFCD00079314
[MOL File]

52050-17-6.mol
[Molecular Weight]

461.63
Chemical PropertiesBack Directory
[Melting point ]

>136°C (dec.)
[storage temp. ]

−20°C
[solubility ]

DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
[form ]

Solid
[color ]

White to Off-White
[BRN ]

4333674
[Stability:]

Hygroscopic
Safety DataBack Directory
[Hazard Codes ]

B
[WGK Germany ]

3
[HS Code ]

2932990090
Hazard InformationBack Directory
[Chemical Properties]

Light Brown Residue
[Uses]

A sphingosine derivative. A sphingolipid compound found in the the umbilical cord artery of women with preeclampsia.
[Uses]

Glucosyl(β) Sphingosine (d18:1) or D-glucosyl-β1-1′-D-erythro-sphingosine may be used:
  • to screen lipids that rapidly and reversibly alter?transepithelial?electrical resistance (TER) or tight junction (TJ) permeability in epithelial tissue
  • as a standard for the quantification of glucosyl sphingosine?in Gaucher patients using liquid chromatography electrospray ionization tandem mass spectrometric (LC/ESI-MS/MS)
  • as an internal standard for the quantification of lysoglucosylceramide in plasma for Gaucher disease using liquid chromatography with tandem mass spectrometry (LC-MS/MS)

[Definition]

ChEBI: Beta-D-glucosylsphingosine is d-Glucosylsphingosine in which the anomeric configuration of the glucosyl moiety is beta. It is a D-glucosylsphingosine and a beta-D-glucoside. It is a conjugate base of a beta-D-glucosylsphingosine(1+).
[General Description]

Glucosyl?sphingosine is a lyso derivative of glucosylceramide (GlcCer).
[Biochem/physiol Actions]

Glucosyl?sphingosine is a potential biomarker for Gaucher′s?disease.?It modulates?Ca2+?release?in the brain?microsomes.
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