| Identification | Back Directory | [Name]
SESELIN | [CAS]
523-59-1 | [Synonyms]
Sesalin
8,8-dimethylpyrano[2,3-f]chromen-2-one
8,8-dimethylpyrano[2,3-h]chromen-2-one
2,2-Dimethyl-1,5-dioxaphenanthrene-6(2H)-one
8,8-Dimethyl-2H,8H-pyrano[2,3-f]chromen-2-one
8,8-Dimethyl-2H,8H-benzo[1,2-b:3,4-b']dipyran-2-one
2H,8H-Benzo[1,2-b:3,4-b']dipyran-2-one, 8,8-dimethyl- | [Molecular Formula]
C14H12O3 | [MDL Number]
MFCD01018179 | [MOL File]
523-59-1.mol | [Molecular Weight]
228.24 |
| Chemical Properties | Back Directory | [Melting point ]
119-124 °C | [Boiling point ]
403.0±45.0 °C(Predicted) | [density ]
1.351 g/cm3(Temp: 18 °C) | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
A solid | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Seselin is a coumarin compound that can be isolated from the root bark of the Citropsis articulata plant. Studies show that Seselin might exhibit potential antimalarial activity and that its derivatives may exhibit antithrombotic activity. | [Definition]
ChEBI: A natural product found in Citropsis articulata. | [Biological Activity]
Seselin is an anti-inflammatoryanti-parasitic and antifungal pyrancoumarin found in anise and other plants. It appears th at seselin targets Jak2 to block the proinflammatory phenotype of macrophages in models of sepsis. Seselin down-regulates levels of proinflammatory factors and activity of STAT1 and p65 in models of sepsis. |
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