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52510-53-9

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52510-53-9 Structure

52510-53-9 Structure
IdentificationBack Directory
[Name]

tetranor-PGAM
[CAS]

52510-53-9
[Synonyms]

tetranor-PGAM
tetranor-PGAM Exclusive
HYPIFMOQVFWSBF-WCQYABFASA-N
tetranor-prostaglandin A metabolite
2-Cyclopentene-1-octanoic acid, 5-(2-carboxyethyl)-ε,4-dioxo-, (1S,5R)-
[Molecular Formula]

C16H22O6
[MOL File]

52510-53-9.mol
[Molecular Weight]

310.35
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
Safety DataBack Directory
[Symbol(GHS) ]


GHS02,GHS07
[Signal word ]

Danger
[Hazard statements ]

H225-H319-H336
[Precautionary statements ]

P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501
Hazard InformationBack Directory
[Description]

Prostaglandin E2 (PGE2), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE2 in biological samples is difficult. The major urinary metabolite of PGE2, tetranor-PGEM, serves as an indirect marker of PGE2 biosynthesis. Though like PGE2, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a surrogate for tetranor-PGEM levels in urine.
[Definition]

ChEBI: Tetranor-PGAM is an oxo carboxylic acid.
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