| Identification | Back Directory | [Name]
6 beta-hydroxycortisol | [CAS]
53-35-0 | [Synonyms]
(6β,11β)-
NSC 76163
Hydrocortisone IMpurity D
6-β-Hydroxy Hydrocortisone
Hydrocortisone EP Impurity D
6,17-Dihydroxycorticosterone
Hydrocortisone impurity D (EP)
6beta,11beta,17,21-Tetrahydroxypreg
6,11,17a,21-Tetrahydroxypregn-4-en-3,20-dione
(6,11)-6,11,17,21-Tetrahydroxypregn-4-ene-3,20-dione
Hydrocortisone Impurity 4（Hydrocortisone EP Impurity D）
Pregn-4-ene-3,20-dione, 6,11,17,21-tetrahydroxy-, (6β,11β)-
Hydrocortisone EP Impurity D (6β-Hydroxycortisol/ 6β-Hydroxyhydrocortisone)
(6R,8S,9S,10R,11S,13S,14S,17R)-6,11,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-diMethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one | [Molecular Formula]
C21H30O6 | [MDL Number]
MFCD00200405 | [MOL File]
53-35-0.mol | [Molecular Weight]
378.46 |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White to Pale Yellow Solid | [Uses]
A metabolite of Cortisol | [Definition]
ChEBI: 6beta-hydroxycortisol is a C21-steroid that is cortisol bearing an additional hydroxy substituent at the 6beta-position. In humans, it is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. It has a role as a mammalian metabolite, a human metabolite and a probe. It is a C21-steroid, a 6beta-hydroxy steroid, a 3-oxo-Delta(4) steroid, a 21-hydroxy steroid, a 20-oxo steroid, a 17alpha-hydroxy steroid, an 11beta-hydroxy steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It is functionally related to a cortisol. |
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