| Identification | Back Directory | [Name]
METHANTHELINE BROMIDE | [CAS]
53-46-3 | [Synonyms]
mtb51
sc2910
ulcine
avagal
banthin
vagamin
metaxan
asabaine
Bantosal
metantyl
vagantin
banthine
doladene
xanteline
methanide
methelina
mantheline
ulcudexter
resobantin
gastrosedan
frenogastrico
Methantheline
Ulcine Bromide
banthinebromide
Dixamone bromide
methanthinebromide
methanthelinebromide
methantheliniumbromide
METHANETHELINIUMBROMIDE
METHANTHELINE BROMIDE (200 MG)
Methantheline Bromide (1401001)
beta-diethylaminoethyl9-xanthenecarboxylatemethobromide
beta-diethylaminoethylxanthene-9-carboxylatemethobromide
diethyl(2-hydroxyethyl)methylammoniumbromidexanthene-9-carboxylate
diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium bromide
diethyl-methyl-[2-(9H-xanthen-9-ylcarbonyloxy)ethyl]azanium bromide
diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]ammonium bromide
ammonium,diethyl(2-hydroxyethyl)methyl-,bromide,xanthene-9-carboxylate
n,n-diethyl-n-methyl-2-((9h-xanthen-9-ylcarbonyl)oxy)-ethanaminiubromide
xanthene-9-carboxylicacid,esterwithdiethyl(2-hydroxyethyl)methylammonium | [EINECS(EC#)]
200-176-0 | [Molecular Formula]
CH3- | [MDL Number]
MFCD00031733 | [MOL File]
53-46-3.mol | [Molecular Weight]
15.0345 |
| Chemical Properties | Back Directory | [Melting point ]
175-176° | [density ]
1.3380 (rough estimate) | [refractive index ]
1.6200 (estimate) | [storage temp. ]
-20°C Freezer, Under inert atmosphere | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Dark Orange to Very Dark Orange |
| Hazard Information | Back Directory | [Uses]
METHANTHELINE BROMIDE is a strong muscarinic receptor blocking drug used in the treatment of overactive bladder syndrome, hypersalivation and hyperhidrosis.
| [Uses]
Ulcine is a strong muscarinic receptor blocking drug used in the treatment of overactive bladder syndrome, hypersalivation and hyperhidrosis. | [Definition]
ChEBI:Methantheline bromide is a member of xanthenes. | [General Description]
Methanthelinebromide, diethyl(2-hydroxyethyl)methylammonium bromidexanthene-9-carboxylate (Banthine Bromide), is awhite, slightly hygroscopic, crystalline salt that is solublein water to produce solutions with a pH of about 5.Aqueous solutions are not stable and hydrolyze in a fewdays. The bromide form is preferable to the very hygroscopicchloride.
Among the conditions for which methantheline bromideis indicated are gastritis, intestinal hypermotility, bladderirritability, cholinergic spasm, pancreatitis, hyperhidrosis,and peptic ulcer, all of which are manifestations ofparasympathotonia. | [Clinical Use]
Methantheline bromide, introduced in 1950, is a potent anticholinergicagent and acts at the nicotinic cholinergic receptors of thesympathetic and parasympathetic systems, as well as at themyoneural junction of the postganglionic cholinergic fibers.Like other quaternary ammonium drugs, methantheline bromideis absorbed incompletely from the GI tract. |
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| Company Name: |
BOC Sciences
|
| Tel: |
|
| Website: |
https://www.bocsci.com |
| Company Name: |
Whyte Chemicals
|
| Tel: |
+44 (20) 8346-5946 |
| Website: |
www.whytechemicals.co.uk |
| Company Name: |
Leancare Ltd.
|
| Tel: |
+33 962096793 |
| Website: |
www.leancare.co.uk |
|