ChemicalBook--->CAS DataBase List--->536-08-3

536-08-3

536-08-3 Structure

536-08-3 Structure
IdentificationBack Directory
[Name]

DIGALLIC ACID
[CAS]

536-08-3
[Synonyms]

Digallate
NSC 59263
m-digallicacid
3-galloylgallicacid
gallicacid,3-gallate
M-Galloylgallic Acid
3-O-Galloylgallic acid
gallicacid3-monogallate
5-Galloyloxyprotocatechuic acid
3,4-dihydroxy-5-((3,4,5-trihydroxybenzoyl)oxy)-benzoicaci
3,4-dihydroxy-5-((3,4,5-trihydroxybenzoyl)oxy)benzoicacid
[EINECS(EC#)]

208-624-7
[Molecular Formula]

C14H10O9
[MDL Number]

MFCD00068961
[MOL File]

536-08-3.mol
[Molecular Weight]

322.224
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[Melting point ]

267-269°C
[Boiling point ]

420.86°C (rough estimate)
[density ]

1.5467 (rough estimate)
[refractive index ]

1.7770 (estimate)
[storage temp. ]

-20°C Freezer
[solubility ]

DMSO: Soluble; Methanol: Soluble
[form ]

A solid
[pka]

4.11±0.10(Predicted)
[Water Solubility ]

0.5g/L(25 ºC)
[Stability:]

Hygroscopic
[LogP]

1.970 (est)
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Description]

Digallic acid is a natural polyphenolic that can be produced by hydrolysis of gallotannins. Like other polyphenolic compounds, digallic acid has antioxidant activity that can be cytoprotective. Digallic acid inhibits reverse transcriptases from human immunodeficiency virus (Ki = 0.58 μM) and murine leukemia virus. It also inhibits calcium-activated chloride channels, blocking the initial agonist-stimulated chloride current.
[Uses]

Digallic Acid is an intermolecular ester of Gallic acid (G188900), a phenolic acid with antioxidant activity. Gallic acid was found to protect human cells against oxidative damage and showed cytotoxicity against cancer cells. Gallic Acid and its esters also show antiviral and antifungal activities.
[Definition]

ChEBI: Digallic acid is a benzoate ester and a gallate ester. It is functionally related to a gallic acid. It is a conjugate acid of a digallate.
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