| Identification | Back Directory | [Name]
norfenefrine | [CAS]
536-21-0 | [Synonyms]
Normetol
Normezaton
Brn 1211018
Metacardiol
m-Octopamine
norfenefrine
Metaoctopamine
DL-m-Octopamine
Normetasympathol
NORFENEFRINEBASE
Einecs 208-626-8
(+-)-m-Octopamine
Normetasynephrine
DL-Norphenylephrine
(+-)-Norphenylephrine
p-Hydroxynoradrenaline
Norfenefrine Impurity A
4779-94-6 (Hydrochloride)
m-Hydroxyphenylethanolamine
1-(3-Hydroxyphenyl)-2-aminoethanol
1-(m-Hydroxyphenyl)-2-aminoethanol
DL-1-(3-Hydroxyphenyl)-2-aminoethanol
dl-1-(m-Hydroxyphenyl)-2-aminoethanol
Etilefrine hydrochloride EP Impurity C
a-(Aminomethyl)-m-hydroxybenzyl alcohol
Benzenemethanol, α-(aminomethyl)-3-hydroxy-
alpha-(Aminomethyl)-m-hydroxybenzyl alcohol
rac-(R*)-2-Amino-1-(3-hydroxyphenyl)ethanol
1-(3-Hydroxyphenyl)-1-hydroxy-2-aminoethane
alpha-(AMinoMethyl)-3-hydroxybenzeneMethanol
Benzyl alcohol, alpha-(aminomethyl)-m-hydroxy-
Benzenemethanol, a-(aminomethyl)-3-hydroxy- (9CI)
Benzyl alcohol, a-(aminomethyl)-m-hydroxy- (6CI, 8CI) | [EINECS(EC#)]
208-626-8 | [Molecular Formula]
C8H11NO2 | [MDL Number]
MFCD00215852 | [MOL File]
536-21-0.mol | [Molecular Weight]
153.18 |
| Chemical Properties | Back Directory | [Melting point ]
75-77 °C | [Boiling point ]
276.1°C (rough estimate) | [density ]
1.1577 (rough estimate) | [refractive index ]
1.5010 (estimate) | [pka]
pKa 8.67(H2O,t undefined,I undefined) (Uncertain) |
| Hazard Information | Back Directory | [Originator]
Zordel,Grelan,Japan,1970 | [Definition]
ChEBI: Norfenefrine is a member of phenols. | [Manufacturing Process]
100 parts of the hydrochloride of meta-hydroxy-ω-aminoacetophenone of melting point 220°C to 222°C (obtainable by brominating metaacetoxyacetophenone, causing the bromoketone to react with sodium iodide, adding hexamethylenetetramine to the iodide in an indifferent solvent and scission of the addition product in acid solution) are shaken in aqueous solution with hydrogen in presence of 2 parts of palladium catalyst until 2 atomic proportions of hydrogen have been absorbed. The catalyst is now filtered and the filtrate evaporated in a vacuum; and the crystalline and completely dry residue is dissolved in absolute alcohol and a precipitate is produced by adding dry ether. The hydrochloride of metahydroxyphenylethanolamine thus obtained forms white crystals of melting point 159°C to 160°C.
| [Therapeutic Function]
Adrenergic |
|
| Company Name: |
Leancare Ltd.
|
| Tel: |
+33 962096793 |
| Website: |
www.leancare.co.uk |
|