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53648-31-0

53648-31-0 Structure

53648-31-0 Structure
IdentificationBack Directory
[Name]

(S)-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride
[CAS]

53648-31-0
[Synonyms]

(S)-nefopam hydrochloride
(S)-3,4,5,6-tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine hydrochloride
[EINECS(EC#)]

258-684-3
[Molecular Formula]

C17H20ClNO
[MOL File]

53648-31-0.mol
[Molecular Weight]

289.8
Chemical PropertiesBack Directory
[solubility ]

DMSO (Sparingly), Water (Slightly)
[form ]

Solid
[color ]

Pale Red to Light Red
Hazard InformationBack Directory
[Uses]

(+)-Nefopam inhibits the uptake of 5-hydroxytryptamine (5-HT), noradrenaline and dopamine in synaptosomal preparations from rat forebrain, hippocampus and striatum. A cyclized analog of orphenadrine and diphenhydramine; representative of a new class of centrally acting skeletal muscle relaxants, the benzoxazocines. Analgesic; antidepressant.
[Definition]

ChEBI: A hydrochloride obtained by reaction of (S)-nefopam with one equivalent of hydrochloric acid (the racemic salt is an analgesic drug).
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