| Identification | Back Directory | [Name]
EVERNIC ACID | [CAS]
537-09-7 | [Synonyms]
Nsc81164
EVERNIC ACID
LECANORIC ACID METHYL ETHER
EVERNIC ACID YELLOW CRYSTALS
orsellinic acid 4-everninate
Wln: qr cq E1 dvovr bq F1 do1
4-[(4-methoxy-6-methylsalicyloyl)oxy]-6-methylsalicylic acid
6-cresoticacid,4-methoxy-4-esterwith6-methyl-beta-resorcylate
6-cresoticacid,4-methoxy-4-esterwith6-methyl-beta-resorcylicacid
2,6-Cresotic acid, 4-methoxy-, 4-ester with 6-methyl-.beta.-resorcylate
2-HYDROXY-4-[2-HYDROXY-4-METHOXY-6-METHYLBENZOYLOXY]-6-METHYLBENZOIC ACID
benzoicacid,2-hydroxy-4-((2-hydroxy-4-methoxy-6-methylbenzoyl)oxy)-6-methyl | [EINECS(EC#)]
208-658-2 | [Molecular Formula]
C17H16O7 | [MDL Number]
MFCD00045824 | [MOL File]
537-09-7.mol | [Molecular Weight]
332.3 |
| Chemical Properties | Back Directory | [Melting point ]
166-167°C | [solubility ]
DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 0.5 mg/ml | [form ]
A crystalline solid | [color ]
White to off-white | [LogP]
5.030 (est) |
| Hazard Information | Back Directory | [Description]
Evernic acid is a secondary metabolite produced by some species of lichen that can bind to allosteric sites on the protein surface of FAS-II enzymes and produce antibacterial and antiplasmodial effects. It inhibits two key plasmodial FAS-II enzymes PfFabZ and PfFabI (IC50 = 10.7 and 36.1 μM, respectively) but shows low efficacy against the malaria parasite P. berghei (IC50 = 77.3 μM). | [Definition]
ChEBI: 2-hydroxy-4-[(2-hydroxy-4-methoxy-6-methylphenyl)-oxomethoxy]-6-methylbenzoic acid is a carbonyl compound. |
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