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537-12-2

537-12-2 Structure

537-12-2 Structure
IdentificationBack Directory
[Name]

DIPERODON HYDROCHLORIDE
[CAS]

537-12-2
[Synonyms]

Proctodon
Diperocaine
Diperodon HCl
diothanehydrochloride
DIPERODON HYDROCHLORIDE
3-piperidino-1,2-propanedioldicarbanilatehydrochloride
3-(1-PIPERIDINYL)-1,2-PROPANEDIOL BIS(PHENYLCARBAMATE)
1,2-propanediol,3-piperidino-,dicarbanilate,hydrochloride
3-(1-piperidyl)-1,2-propanedioldicarbanilatehydrochloride
3-[1-PIPERIDINYL]-1,2-PROPANEDIOL BIS[PHENYLCARBAMATE] HYDROCHLORIDE
1,2-propanediol,3-(1-piperidinyl)-,bis(phenylcarbamato)(ester),monohydroc
[EINECS(EC#)]

208-659-8
[Molecular Formula]

C22H28ClN3O4
[MDL Number]

MFCD00083307
[MOL File]

537-12-2.mol
[Molecular Weight]

433.93
Chemical PropertiesBack Directory
[Melting point ]

193-201°C
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Methanol (Slightly)
[form ]

neat
[color ]

White
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-37/39
[WGK Germany ]

3
[RTECS ]

TZ1101000
Hazard InformationBack Directory
[Originator]

Diothane Hydrochloride,HMR
[Uses]

analgesic, antipyretic, antiinflammatory
[Manufacturing Process]

15.0 g phenylisocyanate in 100 ml of anhydrous ether are added to 10 g of N- (1,2-dihydroxypropyl)-piperidine (prepared from glycide and piperidine) and the solution boiled for two hours, after which it is cooled and saturated with dry hydrogen chloride gas. The ether layer is then decanted off and the remaining insoluble product is dissolved in a hot mixture of acetone and ethyl acetate which on cooling precipitates white crystals of the hydrochloride of the ester of 1,2-propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate); MP 197°- 198°C. A base form may be prepared by adding an equivalent of triethyl amine.
[Therapeutic Function]

1,2-Propanediol, 3-(1-piperidinyl)-, bis(phenylcarbamate) (ester), hydrochloride
[storage]

Store at -20°C
Spectrum DetailBack Directory
[Spectrum Detail]

DIPERODON HYDROCHLORIDE(537-12-2)MS
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