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537-17-7

537-17-7 Structure

537-17-7 Structure
IdentificationBack Directory
[Name]

Amanozine
[CAS]

537-17-7
[Synonyms]

W1191-2
W 1191-2
W-1191-2
Amenozin
Amanozina
Amanozine
Amanozinum
2-Amino-4-anilino-s-triazine
2-Amino-4-anilino-1,3,5-triazin
N-Phenyl-1,3,5-triazine-2,4-diamine
(4-amino-s-triazin-2-yl)-phenyl-amine
2-N-phenyl-1,3,5-triazine-2,4-diamine
1,3,5-Triazine-2,4-diamine, N2-phenyl-
[Molecular Formula]

C9H9N5
[MDL Number]

MFCD00151366
[MOL File]

537-17-7.mol
[Molecular Weight]

187.2
Chemical PropertiesBack Directory
[Melting point ]

235-236°
[Boiling point ]

311.95°C (rough estimate)
[density ]

1.2986 (rough estimate)
[refractive index ]

1.6900 (estimate)
[pka]

3.79±0.10(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]


GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H335-H319
[Precautionary statements ]

P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P
Hazard InformationBack Directory
[Originator]

Amanozine,Onbio Inc.
[Definition]

ChEBI: Amanozine is a diamino-1,3,5-triazine.
[Manufacturing Process]

21.3 g (0.1 mole) of 1-phenylbiguanide hydrochloride were dissolved in hot water and the solution was added to 5.3 g (0.05 mole) sodium carbonate by stirring. On cooling 15 g of the needle crystals have fallen. They were heated to reflux with 80 ml of dry formic acid. Then 40-50 ml formic acid was distilled off. The residue was with water diluted, cooled with ice and the conc. alkali was added. The precipitate fallen. It was filtered off and recrystallized from 40-50% ethanol. The pure product 4-amino-2-anilino-1,3,5-triazine had MP: 232°-233°C.
Monochlorohydrate of it crystallized as long colorless needles melted at 258°- 260°C.
[Therapeutic Function]

Diuretic
[Purification Methods]

It crystallises from dioxane or 50% aqueous EtOH. [Beilstein 26 III/IV 1195.]
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