| Identification | Back Directory | [Name]
5-Chloro-2-nitrobenzenesulfonic acid | [CAS]
54481-12-8 | [Synonyms]
5-Chloro-2-nitrobenzenesulfonic acid
2-nitro-5-chlorobenzenesulfonic acid
Benzenesulfonic acid, 5-chloro-2-nitro- | [Molecular Formula]
C6H4ClNO5S | [MOL File]
54481-12-8.mol | [Molecular Weight]
237.62 |
| Hazard Information | Back Directory | [Physical properties]
5-Chloro-2-nitrobenzenesulfonic Acid, forms hygroscopic crystals of the monohydrate.
| [Uses]
Reduction of 5-Chloro-2-nitrobenzenesulfonic acid gives 4-chloroaniline-2-sulfonic acid, and amination results in 4- nitroaniline-3-sulfonic acid, both of minor importance as intermediates. The derived sulfonyl chloride leads to 5-chloro-2-nitrobenzenesulfonamide, an intermediate in the production of the benzothiadiazine derivative diazoxide, used as a vasodilator.
| [Production Methods]
5,5' -Dichloro-2,2' -dinitrodiphenyldisulfide (obtained from the reaction of 2,4-dichloronitrobenzene with Na2S2) is oxidatively chlorinated with chlorine in HCl – HNO3 to give the sulfonyl chloride, which hydrolyzes to 5-Chloro-2-nitrobenzenesulfonic acid.
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