ChemicalBook--->CAS DataBase List--->54767-75-8

54767-75-8

54767-75-8 Structure

54767-75-8 Structure
IdentificationBack Directory
[Name]

SULOCTIDIL
[CAS]

54767-75-8
[Synonyms]

cp556s
Eusedon
Sulocton
suloctidyl
SULOCTIDIL
erythro-benzylalcoho
erythro-1-(4-isopropylthiophenyl)-2-n-octylaminopropanol
Suloctidil,Inhibitor,Na+/K+ ATPase,inhibit,Sodium potassium pump
erythro-p-(isopropylthio)-alpha-(1-(octylamino)ethyl)benzylalcohol
(R*,S*)-4-[isopropylthio]-alpha-[1-(octylamino)ethyl]benzyl alcohol
(r*,s*)-4-((1-methylethyl)thio)-alpha-(1-(octylamino)ethyl)benzenemethanol
benzenemethanol,4-((1-methylethyl)thio)-alpha-(1-(octylamino)ethyl)-,(r*,s*
Benzenemethanol, 4-[(1-methylethyl)thio]-α-[(1R)-1-(octylamino)ethyl]-, (αS)-
[EINECS(EC#)]

259-332-1
[Molecular Formula]

C20H35NOS
[MDL Number]

MFCD00238751
[MOL File]

54767-75-8.mol
[Molecular Weight]

337.56
Chemical PropertiesBack Directory
[Melting point ]

62.5°C
[Boiling point ]

467.3±35.0 °C(Predicted)
[density ]

0.9880 (rough estimate)
[refractive index ]

1.5800 (estimate)
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

neat
[pka]

13.91±0.20(Predicted)
[color ]

Off-White
Safety DataBack Directory
[Hazard Codes ]

Xn
[Risk Statements ]

22
[Safety Statements ]

36
[WGK Germany ]

3
[RTECS ]

DO8910000
Hazard InformationBack Directory
[Uses]

Vasodilator (peripheral).
[Definition]

ChEBI: (1S,2R)-2-(octylamino)-1-[4-(propan-2-ylthio)phenyl]-1-propanol is an alkylbenzene.
[Brand name]

Bemperil;Cerebro;Circleton;Cp 556s;Dulasi;Duloctil;Euvasal;Farectil;Fluversin;Fluvisco;Hemoantin;Iangene;Ibisul;Loctidon;Metactiv;Octamet;Polivasal;Sudil;Sulc;Sulodene;Suloktil;Sutidil;Tamid;Vascudil.
[World Health Organization (WHO)]

Suloctidil, a peripheral vasodilator, was introduced in 1975 for the treatment of arterial disease. By 1985 its use had been associated with serious adverse effects, including deaths from hepatitis. In July 1985 renewal for approval was refused in the Federal Republic of Germany. This was followed by the voluntary withdrawal of the drug by the manufacturer firstly in several European countries and ultimately on a worldwide basis.
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