| Identification | Back Directory | [Name]
CIS-4-AMINOCROTONIC ACID | [CAS]
55199-25-2 | [Synonyms]
Afatinib Impurity 143
(Z)-4-aminobut-2-enoic acid
2-Butenoic acid, 4-amino-, (2Z)-
4-Amino-cis-2-butenoic acid, CACA
CIS-4-AMINOCROTONIC ACID (CACA) \ GABAC RECEPTOR AGONIST | [Molecular Formula]
C4H7NO2 | [MDL Number]
MFCD00210183 | [MOL File]
55199-25-2.mol | [Molecular Weight]
101.1 |
| Chemical Properties | Back Directory | [Melting point ]
144-145 °C | [Boiling point ]
300.4±25.0 °C(Predicted) | [density ]
1.169±0.06 g/cm3(Predicted) | [solubility ]
H2O: 124 mg/mL | [form ]
solid | [pka]
2.55±0.25(Predicted) | [color ]
white |
| Hazard Information | Back Directory | [Uses]
cis-4-Aminocrotonic acid has been used to study its effect on the spontaneous contractions and muscular relaxation of the longitudinal smooth muscle in mouse duodenum. It has also been used as a γ-aminobutyric acid C (GABAC) receptor agonist to study its effect on radial neuronal migration. | [Biochem/physiol Actions]
cis-4-Aminocrotonic acid (CACA) is a γ-aminobutyric acid C (GABAC) receptor agonist. It is known to induce antinociception in the condition of prostaglandin E2 (PGE2)-induced hyperalgesia. |
|
| Company Name: |
SIGMA-RBI
|
| Tel: |
800 736 3690 (Orders) |
| Website: |
www.sigma-aldrich.com |
|