| Identification | Back Directory | [Name]
Dimethocaine Hydrochloride | [CAS]
553-63-9 | [Synonyms]
Larocaine HCl
diMethocaine hcl
Dimethyl hydrochloride
Larocaine hydrochloride
Dimethocaine hydrochloride
Dimethocaine/Larocaine hcl
Dimethylcaine hydrochloride
Dimethocaine Hydrochloride (1.0 mg/mL in Methanol)
Anesthetic Procaine Benzocaine Levobupivacaine Orphenadrine
DiethylaMinoneopentyl Alcohol Hydrochloride p-AMinobenzoate
3-DiethylaMino-2,2-diMethylpropyl p-aMinobenzoate Hydrochloride
China Factroy Supply 99% Pure Dimethocaine Hydrochloride Powder
3-(DiethylaMino)-2,2-diMethyl-1-propanol 1-(4-aMinobenzoate) HCl
1-AMinobenzoyl-2,2-diMethyl-3-diethylaMinopropanol Hydrochloride
3-(DiethylaMino)-2,2-diMethylpropyl 4-aMinobenzoate hydrochloride
3-(Diethylamino)-2,2-dimethyl-1-propanol 4-aminobenzoate hydrochloride
3-(diethylaMino)-2,2-diMethyl-1-Propanol 1-(4-aMinobenzoate) hydrochloride
1-Propanol, 3-(diethylaMino)-2,2-diMethyl-, 1-(4-aMinobenzoate), hydrochloride
1-Propanol, 3-(diethylamino)-2,2-dimethyl-, 1-(4-aminobenzoate), hydrochloride (1:1) | [EINECS(EC#)]
202-303-5 | [Molecular Formula]
C16H26N2O2.ClH | [MDL Number]
MFCD01697031 | [MOL File]
553-63-9.mol | [Molecular Weight]
314.854 |
| Chemical Properties | Back Directory | [Melting point ]
195-196℃ | [storage temp. ]
Refrigerator | [solubility ]
DMSO (Slightly), Water (Slightly) | [form ]
Solid | [color ]
White to Pale Beige | [InChI]
InChI=1S/C16H26N2O2.ClH/c1-5-18(6-2)11-16(3,4)12-20-15(19)13-7-9-14(17)10-8-13;/h7-10H,5-6,11-12,17H2,1-4H3;1H | [InChIKey]
WWTWKTDXBNHESE-UHFFFAOYSA-N | [SMILES]
C1(=CC=C(N)C=C1)C(=O)OCC(C)(C)CN(CC)CC.Cl |
| Hazard Information | Back Directory | [Chemical Properties]
Off-White Solid | [Uses]
A local anesthetic with stimulant properties. Studies have shown its potency to be about half that of Cocaine (C633500). | [Uses]
Dimethocaine Hydrochloride is a local anesthetic, because of its similarity in action to cocaine, has potential for abuse. This compound completely inhibits dopamine uptake in rat striatal synaptosomes with an IC50 value of 1.2 μM comparable to that of cocaine (IC50 = 0.7 μM). As a result, dimethocaine dose-dependently substitutes for cocaine in drug discrimination tests in rats and rhesus monkeys. This product is intended for forensic and research purposes.[Cayman Chemical]
| [Application]
Dimethocaine Hydrochloride is a drug that belongs to the amide class. It has been shown to have significant effects on neuronal function in vivo, as well as on dopamine neurotransmission in vitro. It is also a substrate for uptake by the dopamine transporter and can inhibit locomotor activity in rats, suggesting it may be a potential therapeutic agent for the treatment of Parkinson's disease. It has been shown to be effective against cocaine addiction and can reduce angiogenic factors in vivo. The drug also interacts with other drugs, including synthetic cannabinoids and amphetamines, which are metabolized by CYP2B6 enzymes. These interactions may result in reduced efficacy of Dimethocaine Hydrochloride therapy. | [Side effects]
Its positive effects are euphoria, stimulation, increased talkativeness and mood lift. However, because the drug acts similar as cocaine, it has comparable negative side effects. These side effects include: tachycardia, difficulty with breathing, pain on the chest, vasoconstriction, insomnia, paranoia and anxiety. |
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