ChemicalBook--->CAS DataBase List--->5534-02-1

5534-02-1

5534-02-1 Structure

5534-02-1 Structure
IdentificationBack Directory
[Name]

BETAMETHASONE BUTYRATE PROPIONATE
[CAS]

5534-02-1
[Synonyms]

Salex
Antebate
Anflavate
BETAMETHASONE BUTYRATE PROPIONATE
Betamethasone 17-butyrate 21-propionate
9-Fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-butyrate 21-propionate
Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16-methyl-17-(1-oxobutoxy)-21-(1-oxopropoxy)-,(11b,16b)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17-(1-oxobutoxy)-21-(1-oxopropoxy)-, (11β,16β)-
[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate
[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyethanoyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate
butyric acid [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-3-keto-10,13,16-trimethyl-17-(2-propionyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] ester
[Molecular Formula]

C29H39FO7
[MDL Number]

MFCD00865998
[MOL File]

5534-02-1.mol
[Molecular Weight]

518.61
Chemical PropertiesBack Directory
[Melting point ]

approximate 152℃
[Boiling point ]

613.0±55.0 °C(Predicted)
[density ]

1.23±0.1 g/cm3(Predicted)
[storage temp. ]

-20°C Freezer, Under inert atmosphere
[solubility ]

Chloroform (Slightly), Dioxane (Slightly, Sonicated), Methanol (Slightly)
[form ]

Solid
[pka]

12.88±0.70(Predicted)
[color ]

White to Off-White
Hazard InformationBack Directory
[Description]

Betamethasone butyrate propionate (BBP) was introduced in Japan as a topical antiinflammatory agent. It is a synthetic corticosteroid with strong antiinflammatory activity at the site of inflammation but without topical or systemic side effects. On paper disk granuloma in rats, BBP was shown to have higher degree of dissociation between antiinflammation efficacy and systemic side effects than other agents in this class. Antipyretic/analgesic properties have also been reported.
[Originator]

Mitsubishi Kasai (Japan)
[Uses]

Betamethasone-17-butyrate-21-propionate are used in the treatment of vitiligo vulgaris with the combination therapy of topical steroid and vitamin D3 compound.
[Definition]

ChEBI: Betamethasone butyrate propionate is a corticosteroid hormone.
[Brand name]

Antebate; Antevate
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