| Identification | Back Directory | [Name]
(R)-(+)-AMINOGLUTETHIMIDE 97 | [CAS]
55511-44-9 | [Synonyms]
CGS-2396
Aminoglutethimide, D-
(R)-(+)-Aminoglutethimide 97%
(R)-(+)-AMINOGLUTETHIMIDE 97
(R)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione
(R)-3-(4-aMinophenyl)-3-ethylpiperidine-2,6-dione
(3R)-3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione
2,6-Piperidinedione, 3-(4-aminophenyl)-3-ethyl-, (3R)- | [Molecular Formula]
C13H16N2O2 | [MDL Number]
MFCD03094025 | [MOL File]
55511-44-9.mol | [Molecular Weight]
232.28 |
| Chemical Properties | Back Directory | [Melting point ]
115.5-119.5 °C (lit.) | [Boiling point ]
457.4±45.0 °C(Predicted) | [density ]
1.173±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
11.60±0.40(Predicted) | [color ]
Off-white to light yellow | [optical activity]
[α]20/D +160°, c = 1 in methanol |
| Hazard Information | Back Directory | [Uses]
(R)-(+)-Aminoglutethimide can be used:
- As a building block for the development of cephalosporin based prodrug for antibody-directed enzyme prodrug therapy (ADEPT).
- To prepare (R)-3-ethyl-3-(4-(3,4,5-trimethoxybenzylamino)phenyl)piperidine-2,6-dione by reacting with 3,4,5-trimethoxybenzylamine via deaminative coupling reaction.
- To synthesize (R)-2-fluoro-2-(4-methoxyphenyl)-N-(R)-(+)-aminoglutethimide by enantioselective α-fluorination.
| [Definition]
ChEBI: The (3R)-enantiomer of aminoglutethimide. |
|
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