ChemicalBook--->CAS DataBase List--->55986-43-1

55986-43-1

55986-43-1 Structure

55986-43-1 Structure
IdentificationBack Directory
[Name]

CETABEN
[CAS]

55986-43-1
[Synonyms]

CETABEN
Peroxisome Proliferator, Cetaben
Benzoic acid, 4-(hexadecylamino)-
HEXADECYLAMINO-P-AMINO BENZOIC ACID
[Molecular Formula]

C23H39NO2
[MDL Number]

MFCD00865766
[MOL File]

55986-43-1.mol
[Molecular Weight]

361.56
Chemical PropertiesBack Directory
[Boiling point ]

503.4±33.0 °C(Predicted)
[density ]

0.979±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

≤1mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
[form ]

crystalline solid
[pka]

4.76±0.10(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Antihyperlipoproteinemic.
[Biological Activity]

cetaben is an unique pparα-independent peroxisome proliferator.the fibrate class of hypolipidemic drugs, such as fenofibrate and clofibrate, elicit their effects via binding to and activating peroxisome proliferator-activated receptor α (pparα).
[in vitro]

previous study showed that cetaben could cause little but reversible proliferation and morphological heterogeneity with the occurrence of dumbbell- and cup-shaped peroxisomal profiles. peroxisomes in hepg2 cells showed marked variation in size and shape. cetaben treatment of hepg2 cells was able to lead to disintegration of golgi regions and augmented mitochondrial matrix [1].
[in vivo]

animal study found that the changes in large scale of liver non-peroxisomal parameters were compared after 10 days administration of both cetaben and clofibric acid 200 mg/kg/day to male wistar rats. no analogical changes were observed after cetaben treatment in the livers of experimental animals. it was also found that both drugs could increase the activities of alanine-glyoxylate aminotransferase-1 and acetylcarnitine transferase--enzymes with proven mitochondrial and peroxisomal location. contrary to clofibric acid, cetaben did not increase solubilization of peroxisomal enzymes [2].
[storage]

Store at -20°C
[References]

[1] kovacs, w. ,walter, i., and stangl, h. cetaben-induced changes on the morphology and peroxisomal enzymes in mh1c1 rat hepatoma and hepg2 human hepatoblastoma cells. histochemistry and cell biology 115, 509-519 (2001).
[2] chandoga, j. ,hampl, l.,turecky, l., et al. cetaben is an exceptional type of peroxisome proliferator. international journal of biochemistry 26(5), 679-696 (1994).
Spectrum DetailBack Directory
[Spectrum Detail]

CETABEN(55986-43-1)1HNMR
55986-43-1 suppliers list
Company Name: ATK CHEMICAL COMPANY LIMITED
Tel: +undefined-21-51877795
Website: www.atkchemical.com
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354 +1-00000000000 , +1-00000000000
Website: https://www.targetmol.com/
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +8618327326525 , +8618327326525
Website: topule.com/
Company Name: Aladdin Scientific
Tel: +1-+1(833)-552-7181
Website: www.aladdinsci.com/
Company Name: Shanghai Boyle Chemical Co., Ltd.  
Tel: 021-50182298 021-50180596
Website: www.boylechem.com
Company Name: AdooQ BioScience, LLC   
Tel: +1 (866) 930-6790
Website: www.adooq.com
Company Name: AdooQ Bioscience CHINA  
Tel: 025-58849295 18951903616;
Website: http://www.adooq.cn
Company Name: BOC Sciences  
Tel: 16314854226
Website: www.bocsci.com
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Tel: 021-65675885 18964387627
Website: http://www.efebio.com
Company Name: Shanghai QianYan Bio-technology Co., Ltd  
Tel: 02781293128
Website: www.chemicalbook.com/ShowSupplierProductsList19348/0.htm
Company Name: ShangHai Biochempartner Co.,Ltd  
Tel: 17754423994 17754423994
Website: https://www.biochempartner.com
Company Name: Cckinase, Inc.  
Tel: +1 (732)236-3202
Website: www.cckinase.com
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Website: www.chemegen.com
Company Name: Shanghai hongqu biomedical technology co. LTD  
Tel: 88888888888
Website: www.chemicalbook.com/ShowSupplierProductsList873228/0.htm
Company Name: MedBioPharmaceutical Technology Inc  
Tel: 021-69568360 18916172912
Website: http://www.med-bio.cn/
Company Name: Wuhan Topule  
Tel: +86-02787215551 +86-19945035818
Website: http://www.topule.com/
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840
Website: www.jm-bio.com/
Company Name: InvivoChem  
Tel: 13549236410
Website: https://www.invivochem.cn/
Tags:55986-43-1 Related Product Information