| Identification | Back Directory | [Name]
1-Cyanotetraline | [CAS]
56536-96-0 | [Synonyms]
1-CyanoTetralin
α-Cyanotetraline
1-CYANO-TETRALINE
Tetralin-1-carbonitrile
Tetryzoline EP Impurity A
a-cyanotetrahydronaphthalene
1-cyano tetrahydronaphthalene
1-Cyano Tetrahydronaphathalene
(1RS)-1,2,3,4-Tetrahydronaphthalene
Tetryzoline Hydrochloride Impurity A
1-Cyano-1,2,3,4-tetrahydronaphthalene
1,2,3,4-Tetrahydro-1-naphthalenecarbonitrile
1-Naphthalenecarbonitrile,1,2,3,4-tetrahydro- | [EINECS(EC#)]
611-399-1 | [Molecular Formula]
C11H11N | [MDL Number]
MFCD08703294 | [MOL File]
56536-96-0.mol | [Molecular Weight]
157.21 |
| Chemical Properties | Back Directory | [Melting point ]
48-50 °C | [Boiling point ]
309 °C | [density ]
1.06 | [refractive index ]
1.55 | [Fp ]
114 °C | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Chloroform (Sparingly), DMSO (Slightly), Ethyl Acetate (Slightly) | [form ]
Oil | [color ]
Colourless to Yellow |
| Hazard Information | Back Directory | [Chemical Properties]
light yellow oil liquid | [Uses]
1-Cyanotetraline is used in the synthesis of aldose reductase inhibitors. Also reductase enzymes are believed to catalyze the formation of sorbitol from glucose leading to the chronic complications of
diabetes mellitus. It is also used in the synthesis of baclofen analogs, potent GABAB agonists. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 99, p. 959, 1977 DOI: 10.1021/ja00445a057
Tetrahedron Letters, 36, p. 4307, 1995 DOI: 10.1016/0040-4039(95)00746-Y |
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