| Identification | Back Directory | [Name]
Vildagliptin Chloroacetyl Nitrile (R)-Isomer | [CAS]
565452-98-4 | [Synonyms]
Vildagliptin Impurity 7
Vildagliptin impurities14
Vildagliptin?Chloroacetyl Nitrile (R)-Isomer
(R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
(R)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
(2R)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile
2-Pyrrolidinecarbonitrile, 1-(2-chloroacetyl)-, (2R)-
2-Pyrrolidinecarbonitrile, 1-(chloroacetyl)-, (2R)- (9CI)
Vildagliptin Impurity 15/Vildagliptin Chloroacetyl Nitrile (R)-Isomer/(1S)-2-(2-chloroacetyl)cyclopentane-1-carbonitrile | [Molecular Formula]
C7H9ClN2O | [MDL Number]
MFCD11215489 | [MOL File]
565452-98-4.mol | [Molecular Weight]
172.61 |
| Chemical Properties | Back Directory | [Melting point ]
64-67°C | [Boiling point ]
363.1±37.0 °C(Predicted) | [density ]
1.27±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
-4.65±0.40(Predicted) | [color ]
White to Pale Yellow |
| Hazard Information | Back Directory | [Uses]
(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes. | [Uses]
(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.
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