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568-53-6

568-53-6 Structure

568-53-6 Structure
IdentificationBack Directory
[Name]

alpha-peltatin
[CAS]

568-53-6
[Synonyms]

a-Peltatin
α-Peltatin
alpha-peltatin
(5R)-5,8,8aβ,9-Tetrahydro-10-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aαH)-one
(5R,5aα)-5,8,8aβ,9-Tetrahydro-10-hydroxy-5β-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one
(5R,5aR,8aR)-10-Hydroxy-5-(4-hydroxy-3,5-dimethoxy-phenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one
Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-10-hydroxy-5-(4-hydroxy-3,5-dimethoxyphenyl)-, (5R,5aR,8aR)-
[Molecular Formula]

C21H20O8
[MDL Number]

MFCD00873738
[MOL File]

568-53-6.mol
[Molecular Weight]

400.381
Chemical PropertiesBack Directory
[alpha ]

D20 -124.8° (c = 0.5 in chloroform)
Hazard InformationBack Directory
[Uses]

α-Peltatin is one of the major lignans in Podophyllum peltatum, and is one of the components of Podophyllin, a complex mixture of oils and pigments that was used as a purgative. α-Peltatin also has biological activity against tumours.
[Definition]

ChEBI: Alpha-peltatin is an organic heterotetracyclic compound that is 4'-demethylpodophyllotoxin which is substituted by a hydroxy group at position 10 but which is lacking the hydroxy group at position 9. It is found as a glucoside in the rhizomes of Podophyllum peltatum. It has a role as a metabolite and an antineoplastic agent. It is a furonaphthodioxole, a gamma-lactone, an organic heterotetracyclic compound, a lignan and a member of phenols.
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