| Identification | Back Directory | [Name]
Galloflavin | [CAS]
568-80-9 | [Synonyms]
NSC 107022
Galloflavin
Galloflavin（NSC-107022）
3,8,9,10-Tetrahydroxypyrano[3,2-C]Isochromene-2,6-Dione
6,8,9,10-tetrahydroxypyrano[3,2-c]isochromene-2,3-dione
3,8,9,10-Tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione
Pyrano[3,2-c][2]benzopyran-2,6-dione, 3,8,9,10-tetrahydroxy-
3,8,9,10-Tetrahydroxy-pyrano[3,2-c][2]benzopyran-2,6-dione,NSC 107022 | [Molecular Formula]
C12H6O8 | [MDL Number]
MFCD26941292 | [MOL File]
568-80-9.mol | [Molecular Weight]
278.17 |
| Chemical Properties | Back Directory | [Melting point ]
>140°C (dec.) | [storage temp. ]
-20°C | [solubility ]
DMSO: soluble5mg/mL, clear | [form ]
powder | [color ]
light yellow to light brown |
| Hazard Information | Back Directory | [Uses]
Galloflavin is a novel inhibitor of lactate dehydrogenase and is a potential anticancer agent. | [Uses]
Galloflavin is a novel inhibitor of lactate dehydrogenase and is a potential anticancer agent. This compound is suitable for lactate dehydrogenase (LDH) related research. | [Biochem/physiol Actions]
Galloflavin is an inhibitor of lactate dehydrogenase (LDH). The compound blocks both isoforms of (LDH-A and –B) with Ki values of 5.5 and 15 μM, respectively. Inhibition of the glycolytic pathway by galloflavin induces oxidative stress and apoptosis in breast tumor cell lines. |
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