ChemicalBook--->CAS DataBase List--->57078-99-6

57078-99-6

57078-99-6 Structure

57078-99-6 Structure
IdentificationBack Directory
[Name]

5-MALEIMIDO VALERIC ACID
[CAS]

57078-99-6
[Synonyms]

MVA
AUN78996
5-MALEIMIDO VALERIC ACID
5-Maleimido-pentanoic acid
5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)
1H-Pyrrole-1-pentanoic acid, 2,5-dihydro-2,5-dioxo-
5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid
[Molecular Formula]

C9H11NO4
[MDL Number]

MFCD04115790
[MOL File]

57078-99-6.mol
[Molecular Weight]

197.19
Chemical PropertiesBack Directory
[Melting point ]

84-85 °C(Solv: ethyl acetate (141-78-6))
[Boiling point ]

400.7±28.0 °C(Predicted)
[density ]

1.334±0.06 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[form ]

Solid
[pka]

4.67±0.10(Predicted)
[color ]

Off-white to yellow
Hazard InformationBack Directory
[Description]

5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
[Uses]

5-Maleimidopentanoic Acid is a potential inhibitor of prostaglandin endoperoxide synthase (PGHS)?.
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