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57229-25-1

57229-25-1 Structure

57229-25-1 Structure
IdentificationBack Directory
[Name]

4-Phospho D-Erythronate
[CAS]

57229-25-1
[Synonyms]

4-Phospho D-Erythronate
(2R,3R)-2,3-Dihydroxy-4-(phosphonooxy)butanoic Acid
[R-(R*,R*)]-2,3-Dihydroxy-4-(phosphonooxy)butanoic Acid
Butanoic acid, 2,3-dihydroxy-4-(phosphonooxy)-, (2R,3R)-
[Molecular Formula]

C4H9O8P
[MOL File]

57229-25-1.mol
[Molecular Weight]

216.08
Chemical PropertiesBack Directory
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

Methanol (Slightly, Water (Slightly)
[form ]

Oil
[color ]

Clear Colorless to Light Yellow
Hazard InformationBack Directory
[Uses]

4-Phospho-D-erythronate is an intermediate in the synthesis of pyridoxal 5''-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Phosphorylated aldonic acids are strong inhibitors of 6-phosphogluconate dehydrogenase, and 4-phospho-D-erythronate (4PE) and 4-phospho-D-erythronohydroxamate are two of the strongest inhibitors of the Trypanosoma brucei enzyme.
[Uses]

4-Phospho-D-erythronate is an intermediate in the synthesis of pyridoxal 5'-phosphate in some bacteria and an inhibitor of ribose 5-phosphate isomerase. Phosphorylated aldonic acids are strong inhibitors of 6-phosphogluconate dehydrogenase, and 4-phospho-D-erythronate (4PE) and 4-phospho-D-erythronohydroxamate are two of the strongest inhibitors of the Trypanosoma brucei enzyme.
[Definition]

ChEBI: 4-phospho-D-erythronic acid is the D-enantiomer of 4-phosphoerythronic acid. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is functionally related to a D-erythronic acid. It is a conjugate acid of a 4-O-phosphonato-D-erythronate(3-). It is an enantiomer of a 4-phospho-L-erythronic acid.
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