| Identification | Back Directory | [Name]
PNU 37883 hydrochloride | [CAS]
57568-80-6 | [Synonyms]
U-37883A
PNU 37883 hydrochlor
PNU 37883 HYDROCHLORIDE
N-CYCLOHEXYL-N'-TRICYCLO[3.3.1.1(3,7)]DEC-1-YL-4-MORPHOLINECARBOXIMIDAMIDE HYDROCHLORIDE | [Molecular Formula]
C21H36ClN3O | [MDL Number]
MFCD03840615 | [MOL File]
57568-80-6.mol | [Molecular Weight]
381.98 |
| Hazard Information | Back Directory | [Biological Activity]
Novel antagonist selective for the vascular form of K ATP channel; inhibits K ATP currents in isolated mesenteric artery smooth muscle cells (K d = 65 nM) but not in cardiac or skeletal myocytes. In vivo, inhibits blood vessel relaxation and hypotension induced by pinacidil. Displays weak diuretic effects. | [storage]
Desiccate at RT |
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