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5843-65-2

5843-65-2 Structure

5843-65-2 Structure
IdentificationBack Directory
[Name]

Demethyl-Coclaurine
[CAS]

5843-65-2
[Synonyms]

Norcoclaurine
(RS)-norcoclaurine
Demethyl-Coclaurine
1-(4-Hydroxybenzyl)
Higenamine - natural
DL-Demethylcoclaurine
HigenaMine HydrobroMide Salt
Demethyl-Coclaurine USP/EP/BP
Higenamine, 98%, from Lindera aggregata (Sims) Kosterm.
1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol
1-[(4-hydroxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinoline-6,7-diol
1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-isoquinolinediol
6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-
[Molecular Formula]

C16H17NO3
[MDL Number]

MFCD01736979
[MOL File]

5843-65-2.mol
[Molecular Weight]

271.314
Chemical PropertiesBack Directory
[Melting point ]

208-210 °C
[Boiling point ]

522.4±50.0 °C(Predicted)
[density ]

1.317±0.06 g/cm3(Predicted)
[storage temp. ]

Refrigerator
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

9.72±0.40(Predicted)
[color ]

White to Off-White
Hazard InformationBack Directory
[Uses]

Demethyl-Coclaurine acts through inhibition of middle cerebral artery occlusion (MCAO)-mediated HMGB1 release in vivo. Useful towards ischemic injuries.
[Definition]

ChEBI: (RS)-norcoclaurine is a norcoclaurine. It is a conjugate base of a (RS)-norcoclaurinium.
[storage]

Store at -20°C
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