ChemicalBook--->CAS DataBase List--->58801-34-6

58801-34-6

58801-34-6 Structure

58801-34-6 Structure
IdentificationBack Directory
[Name]

ETH 1001
[CAS]

58801-34-6
[Synonyms]

CA 1001
ETH 1001
Einecs 261-449-8
CALCIUM IONOPHORE
CALCIUM IONOPHORE I
CA 1001 - CAS 58801-34-6 - Calbiochem
FLUKABRAND SELECTOPHORE, CALCIUM*IONOPHORE I
(4R,5R)-N,N'-Bis[11-(ethoxycarbonyl)undecyl]-N,N',4,5-tetramethyl-3,6-dioxaoctanediamide
(-)-(R,R)-N,N'-[Bis(11-ethoxycarbonyl)undecyl]-N,N',4,5-tetramethyl-3,6-dioxooctanediamide
(-)-(R,R)-N,N'-BIS[11-(ETHOXYCARBONYL)UNDECYL]-N,N',4,5-TETRAMETHYL-3,5-DIOXAOCTANEDIAMIDE
(-)-(R,R)-N,N'-BIS-[11-(ETHOXYCARBONYL)UNDECYL]-N,N'-4,5-TETRAMETHYL-3,6-DIOXAOCTANEDIAMIDE
DIETHYL-N,N'-[(4R,5R)-4,5-DIMETHYL-1,8-DIOXO-3,6-DIOXAOCTAMETHYLENE]BIS(12-METHYLAMINODODECANOATE)
diethyl [R-(R*,R*)]-13,17,18,22-tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontanedioate
Diethyl (R-(R*,R*))-13,17,18,22-tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontanedioate
12,12'-[[(1R,2R)-1,2-Dimethylethylene]bis[oxymethylenecarbonyl(methylimino)]]bisdodecanoic acid diethyl ester
(17R,18R)-13,17,18,22-Tetramethyl-14,21-dioxo-16,19-dioxa-13,22-diazatetratriacontanedioic acid diethyl ester
16,19-Dioxa-13,22-diazatetratriacontanedioic acid, 13,17,18,22-tetramethyl-14,21-dioxo-, diethyl ester, (R-(R*,R*))-
16,19-Dioxa-13,22-diazatetratriacontanedioic acid, 13,17,18,22-tetramethyl-14,21-dioxo-, 1,34-diethyl ester, (17R,18R)-
ETH 1001, (-)-(R,R)-N,Nμ-Bis-[11-(ethoxycarbonyl)undecyl]-N,Nμ,4,5-tetramethyl-3,6-dioxaoctane-diamide, Diethyl N,Nμ-[(4R,5R)-4,5-dimethyl-1,8-dioxo-3,6-dioxaoctamethylene]bis(12-methylaminododecanoate)
[EINECS(EC#)]

261-449-8
[Molecular Formula]

C38H72N2O8
[MOL File]

58801-34-6.mol
[Molecular Weight]

684.99
Chemical PropertiesBack Directory
[Boiling point ]

715.1±50.0 °C(Predicted)
[density ]

1.000±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Soluble in DMSO
[form ]

Light yellow, translucent, highly viscous oil
[pka]

-0.52±0.70(Predicted)
[color ]

Colorless to light yellow
[BRN ]

2343275
Safety DataBack Directory
[WGK Germany ]

3
[F ]

9-23
Hazard InformationBack Directory
[Description]

Calcium ionophore I is a Ca2+-selective ionophore for biological membranes that can be used in microelectrodes for the determination of intracellular Ca2+-activities and of slowly changing Ca2+ levels.
[storage]

Store at -20°C
[Purification Methods]

This is a neutral Ca selectophore. It can be purified by thick layer (2mm) chromatography (Kieselgel F245) and eluted with Me2CO/CHCl3 (2:1). [Ammann et al. Helv Chim Acta 56 1780 1973, Simon & Carafoli Methods Enzymol 56 439 1977.]
[References]

dagostino m, lee co. neutral carrier na+- and ca2+-selective microelectrodes for intracellular application. biophys j. 1982 dec;40(3):199-207.caroni p, gazzotti p, vuilleumier p, et al. ca2+ transport mediated by a synthetic neutral ca2+ -ionophore in biological membranes. biochim biophys acta. 1977 nov 1;470(3):437-45.hinds tr, vincenzi ff. the effect of eth 1001 on ion fluxes across red blood cell membranes. cell calcium. 1985 jun;6(3):265-79.lücke a, lehmenkühler a, speckmann ej. the influence of the convulsant pentylenetetrazol on ca2+-selective microelectrodes (neutral carrier eth 1001). j neurosci methods. 1989 aug;29(2):139-42.lee mh, yoo cl, lee js, et al. tweezer-type neutral carrier-based calcium-selective membrane electrode with drastically reduced anionic interference. anal chem. 2002 jun 1;74(11):2603-7.
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