ChemicalBook--->CAS DataBase List--->59468-85-8

59468-85-8

59468-85-8 Structure

59468-85-8 Structure
IdentificationBack Directory
[Name]

4-HYDROXYMIDAZOLAM
[CAS]

59468-85-8
[Synonyms]

8-Chloro-6-(2-fluorophenyl)-4-hydroxy-4H-imidazo[1,5a][1,4]bezodiazepine
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-o
8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepin-4-ol
4-Hydroxymidazolam,8-Chloro-6-(2-fluorophenyl)-4-hydroxy-4H-imidazo[1,5a][1,4]bezodiazepine
[EINECS(EC#)]

200-323-9
[Molecular Formula]

C18H13ClFN3O
[MDL Number]

MFCD00871459
[MOL File]

59468-85-8.mol
[Molecular Weight]

341.77
Chemical PropertiesBack Directory
[Appearance]

Off-White Solid
[Melting point ]

186-187 °C
[Boiling point ]

550.6±60.0 °C(Predicted)
[density ]

1.44±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[pka]

12.69±0.40(Predicted)
[color ]

white to off-white
[CAS DataBase Reference]

59468-85-8
Hazard InformationBack Directory
[Chemical Properties]

Off-White Solid
[Uses]

A metabolite of Midazolam (M343000).
[Definition]

ChEBI:4-hydroxymidazolam is an imidazobenzodiazepine that is midazolam which is substituted by a hydroxy group at position 4. It is the minor hydroxylated metabolite of the anesthetic, midazolam. It has a role as a drug metabolite, a human blood serum metabolite and a human urinary metabolite. It is an imidazobenzodiazepine, a member of monofluorobenzenes, an organochlorine compound and an organic hydroxy compound. It is functionally related to a midazolam.
[Biochem/physiol Actions]

4′-Hydroxymidazolam is the minor hydroxylated metabolite of Midazolam (MDZ). The product contributes in the pharmacological impact of MDZ.
[storage]

Store at -20°C
Safety DataBack Directory
[WGK Germany ]

3
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