| Identification | Back Directory | [Name]
(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE | [CAS]
59474-01-0 | [Synonyms]
XI-011
NSC 146109
NSC 146109 HYDROCHLORIDE
NSC 146109 (HYDROCHLORIDE);XI-011
XI-011 (NSC 146109 hydrochloride)
S-(10-Methylanthracen-9-yl)methyl Isothiourea Hydrochloride
(10-Methylanthracen-9-yl)methyl Carbamimidothiote Hydrochloride
(10-Methylanthracen-9-yl)methyl carbamimidothioate hydrochloride
(10-METHYL-9-ANTHRACENYL) CARBAMIMIDOTHIOIC ACID METHYL ESTER HYDROCHLORIDE
(10-Methyl-9-anthracenyl) methyl carbamimidothioic acid ester hydrochloride | [Molecular Formula]
C17H17ClN2S | [MDL Number]
MFCD07783997 | [MOL File]
59474-01-0.mol | [Molecular Weight]
316.85 |
| Hazard Information | Back Directory | [Uses]
This molecule inhibits MDMX expression in breast cancer cells through activating p53 resulting in apoptosis in cancer cells. | [Biological Activity]
Cell-permeable, genotype-selective antitumor agent that activates p53-dependent transcription. Increases levels of endogenous p53 in tumor cells and protects p53 from Mdm2-mediated degradation. Displays some selectivity for tumor cells vs. normal cells in an MTT cell viability assay. |
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