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59973-80-7

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59973-80-7 Structure

59973-80-7 Structure
IdentificationBack Directory
[Name]

SULINDAC SULFONE
[CAS]

59973-80-7
[Synonyms]

FGN-1
APTOSYN
Prevatec
EXISULIND
Ccris 7242
Unii-K619iig2R9
SULINDAC SULFONE
APTOSYN/EXISULIND
Sulindac Impurity B
(Z)-Sulindac Sulfone
Sulindac USP Related Compound B
Sulindac EP Impurity B (Sulindac Sulfone)
Sulindac Impurity 2（Sulindac EP Impurity B）
Sulindac EP Impurity B (Sulindac USP Related Compound B, Sulindac Sulfone)
Sulindac EP Impurity B/ Sulindac Related Compound B ((Z)-Sulindac Sulfone)
(Z)-5-FLUORO-2-METHYL-1[P-(METHYLSULFONYL)BENZYLIDENE]INDENE-3-ACETIC ACID
cis-5-Fluoro-2-methyl-1-(p-methylsulfonylbenzylidenyl)indene-3-acetic acid
5-Fluoro-2-methyl-1-[(Z)-4-(methylsulfonyl)benzylidene]-1H-indene-3-acetic acid
(Z)-5-Fluoro-2-Methyl-1-[[4-(Methylsulfonyl)phenyl]Methylene]-1H-indene-3-acetic Acid
1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfonyl)phenyl)methylene)-, (1Z)-
Sulindac Related Compound B ((Z)-2-{5-fluoro-2-methyl-1-[4-(methylsulfonyl)benzylidene]-1H-inden-3- (1642020)
[Molecular Formula]

C20H17FO4S
[MDL Number]

MFCD01317811
[MOL File]

59973-80-7.mol
[Molecular Weight]

372.41
Chemical PropertiesBack Directory
[Melting point ]

248-250°C
[alpha ]

D -62° (c = 1 in CHCl3)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

DMSO: >25 mg/mL
[form ]

solid
[color ]

yellow
[Stability:]

Hygroscopic
Safety DataBack Directory
[WGK Germany ]

3
[HS Code ]

2930902000
Hazard InformationBack Directory
[Chemical Properties]

Yellow Solid
[Uses]

An active metabolite of Sulindac. Inducer of apoptosis independent of cyclooxygenase inhibition. Inhibits cell growth by inducing apoptosis.
[Uses]

Sulindac Sulfone is an inhibitor of growth and inducer of apoptosis in cancer cell lines.
[Definition]

ChEBI: A sulfone metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. It inhibits the development and induces regression of premalignant adenomatous polyps. Lipoxygenase and Cox-2 inhibitor.
Spectrum DetailBack Directory
[Spectrum Detail]

SULINDAC SULFONE(59973-80-7)1HNMR
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