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60117-17-1

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60117-17-1 Structure

60117-17-1 Structure
IdentificationBack Directory
[Name]

Met-enkephalinamide
[CAS]

60117-17-1
[Synonyms]

5-Methionine-enkephalin amide
L-Methioninamide, L-tyrosylglycylglycyl-L-phenylalanyl-
[Molecular Formula]

C27H36N6O6S
[MDL Number]

MFCD00076416
[MOL File]

60117-17-1.mol
[Molecular Weight]

572.68
Chemical PropertiesBack Directory
[Melting point ]

142-145 °C
[Boiling point ]

1066.7±65.0 °C(Predicted)
[density ]

1.303±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

Soluble in DMSO
[pka]

9.97±0.15(Predicted)
Hazard InformationBack Directory
[Uses]

[Met5]-Enkephalin, amide is an agonist for δ opioid receptors as well as putative ζ (zeta) opioid receptors.
[IC 50]

δ Opioid Receptor/DOR
[References]

[1] Stiene-Martin A, et al. Glial growth is regulated by agonists selective for multiple opioid receptor types in vitro. J Neurosci Res. 1991 Aug;29(4):538-48. DOI:10.1002/jnr.490290415
[2] Kennedy C, et al. [Met5]enkephalin acts via delta-opioid receptors to inhibit pelvic nerve-evoked contractions of cat distal colon. Br J Pharmacol. 1987 Oct;92(2):291-8. DOI:10.1111/j.1476-5381.1987.tb11323.x
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