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60504-57-6

60504-57-6 Structure

60504-57-6 Structure
IdentificationBack Directory
[Name]

methyl (1R,2R,4S)-4-[(2S,4S,5S,6S)-4-dimethylamino-5-hydroxy-6-methyl- oxan-2-yl]oxy-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-3,4-dihydro-1H-tetra cene-1-carboxylate
[CAS]

60504-57-6
[Synonyms]

Aklavin
MA-144T1
Ccris 2266
Nsc 100290
Doxypyrromycin
Aclacinomycin T
1-Deoxypyrromycin
Antibiotic ma 144T1
methyl (1R,2R,4S)-4-[(2S,4S,5S,6S)-4-dimethylamino-5-hydroxy-6-methyl- oxan-2-yl]oxy-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-3,4-dihydro-1H-tetra cene-1-carboxylate
(1R)-2-Ethyl-1,2,3,4,6,11-hexahydro-2α,5,7-trihydroxy-6,11-dioxo-4α-[[2,3,6-trideoxy-3-dimethylamino-α-L-lyxo-hexopyranosyl]oxy]naphthacene-1β-carboxylic acid methyl ester
(1R)-2-Ethyl-2α,5,7-trihydroxy-4α-[[3-(dimethylamino)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]-6,11-dioxo-1,2,3,4,6,11-hexahydronaphthacene-1β-carboxylic acid methyl ester
(1R)-2-Ethyl-1,2,3,4,6,11-hexahydro-2α,5,7-trihydroxy-4α-[[3-(dimethylamino)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]-6,11-dioxonaphthacene-1β-carboxylic acid methyl ester
1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-(dimethylamino)-α-L-lyxo-hexopyranosyl]oxy]-, methyl ester, (1R,2R,4S)-
1-Naphthacenecarboxylic acid, 2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-((2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexapyranosyl)oxy)-, methyl ester, (1R-(1-alpha,2-beta,4-beta))-
[Molecular Formula]

C30H35NO10
[MDL Number]

MFCD01939769
[MOL File]

60504-57-6.mol
[Molecular Weight]

569.6
Chemical PropertiesBack Directory
[Boiling point ]

633.08°C (rough estimate)
[density ]

1.2894 (rough estimate)
[refractive index ]

1.6310 (estimate)
Hazard InformationBack Directory
[Uses]

Aklavine is an anthracycline based anticancer antibiotic, in which it is biosynthesized by S-Adenosyl-l-methionine (SAM)-dependent Methyltransferases.
[Definition]

ChEBI: An anthracycline that is aklavinone having an alpha-L-rhodosaminyl residue attached at position 4 via a glycosidic linkage.
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