| Identification | Back Directory | [Name]
HZ166 thyl 8-ethynyl-6-(2-pyridyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate | [CAS]
612527-56-7 | [Synonyms]
HZ166 thyl 8-ethynyl-6-(2-pyridyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylic acid, 8-ethynyl-6-(2-pyridinyl)-, ethyl ester | [Molecular Formula]
C21H16N4O2 | [MDL Number]
MFCD32670717 | [MOL File]
612527-56-7.mol | [Molecular Weight]
356.38 |
| Hazard Information | Back Directory | [Biological Activity]
HZ-166 is a potentnon-sedative GABAA receptor subtype-selective benzodiazepine site agonist exhibits preference toward α2- and α3-GABAARs. HZ-166 exhibits antihyperalgesic properties in mice models of neuropathic and inflammatory painwithout sedation and motor impairment. |
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