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61303-13-7

61303-13-7 Structure

61303-13-7 Structure
IdentificationBack Directory
[Name]

Isoacteoside
[CAS]

61303-13-7
[Synonyms]

Isoacteosid
Isokusaginin
ISOACTEOSIDE
ISOVERBASCOSIDE
Isoacteoside, >=98%
Isoacteoside,HPLC≥98%
Isoacteoside (Isoverbascoside)
3,4-Dihydroxyphenethyl 3-O-α-L-rhamnopyranosyl-6-O-(3,4-dihydroxycinnamoyl)-β-D-glucopyranoside
2-(3,4-Dihydroxyphenyl)ethyl 3-O-α-L-rhamnopyranosyl-6-O-(3,4-dihydroxycinnamoyl)-β-D-glucopyranoside
2-(3,4-Dihydroxyphenyl)ethyl 3-O-(α-L-rhamnopyranosyl)-6-O-[(E)-3-(3,4-dihydroxyphenyl)acryloyl]-β-D-glucopyranoside
2-(3,4-Dihydroxyphenyl)ethyl 3-O-(α-L-rhamnopyranosyl)-6-O-[(E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propenyl]-β-D-glucopyranoside
β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 6-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
[(2R,3R,4S,5R,6R)-5-(3,4-Dihydroxyphenyl)-6-ethoxy-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
[(2R,3R,4S,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-3,5-dihydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
[Molecular Formula]

C29H36O15
[MDL Number]

MFCD06798947
[MOL File]

61303-13-7.mol
[Molecular Weight]

624.59
Chemical PropertiesBack Directory
[Melting point ]

220~230℃
[Boiling point ]

942.9±65.0 °C(Predicted)
[density ]

1.60±0.1 g/cm3(Predicted)
[storage temp. ]

under inert gas (nitrogen or Argon) at 2-8°C
[solubility ]

DMSO : ≥ 48 mg/mL (76.85 mM)
[form ]

Powder
[pka]

9.32±0.10(Predicted)
[color ]

White to yellow
Safety DataBack Directory
[HS Code ]

29389090
Hazard InformationBack Directory
[Description]

Isoverbascoside is a phenylethanoid glycoside that has been found in C. trichotomum and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay and inhibits hydrogen peroxide-induced lipid peroxidation in V79-4 cells when used at a concentration of 10 μg/ml. Isoverbascoside (7.5-30 μM) induces apoptosis and production of reactive oxygen species (ROS) in, and reduces viability of, OVCAR-3 cells. It inhibits tumor growth in an OVCAR-3 mouse xenograft model when administered at a dose of 30 mg/kg. Isoverbascoside (2.5 and 5 mg/kg) decreases brain amyloid deposition and increases exploratory behavior in rats when infused into the cerebral ventricles with amyloid-β (1-42) (Aβ42; Item No. 20574). It also decreases xylene-induced ear edema in mice and increases survival in a mouse model of LPS-induced endotoxic shock.
[Uses]

Isoacteoside is a possible food antioxidant.
[Definition]

ChEBI: Isoacteoside is a hydroxycinnamic acid.
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