| Identification | Back Directory | [Name]
15-keto Prostaglandin A1 | [CAS]
61600-67-7 | [Synonyms]
15-keto PGA1
15-keto Prostaglandin A1
Prosta-10,13-dien-1-oic acid, 9,15-dioxo-, (13E)- (9CI) | [Molecular Formula]
C20H30O4 | [MOL File]
61600-67-7.mol | [Molecular Weight]
334.45 |
| Hazard Information | Back Directory | [Description]
Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. 15-keto PGA1 is a metabolite of PGA1, produced by 15-hydroxy PG dehydrogenase. It can be produced from PGA1 in pig lung, trachea, aorta, and pulmonary artery tissue preparations. 15-keto PGA1, given at a concentration of 6 μM, causes vasoconstriction of rabbit lung that is comparable to that induced by angiotensin II. | [Uses]
15-keto PGA1 is a metabolite of PGA1 (P838545), produced by 15-hydroxy PG dehydrogenase. | [Definition]
ChEBI: 15-dehydroprostaglandin A1 is a member of the class of prostaglandins A obtained by oxidation of the 15-hydroxy group of prostaglandin A1 to the corresponding ketone. It has a role as an Escherichia coli metabolite and a human metabolite. It is functionally related to a prostaglandin A1. It is a conjugate acid of a 15-dehydroprostaglandin A1(1-). |
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