ChemicalBook--->CAS DataBase List--->622867-52-1

622867-52-1

622867-52-1 Structure

622867-52-1 Structure
IdentificationBack Directory
[Name]

tert-butyl 6-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate
[CAS]

622867-52-1
[Synonyms]

2-Boc-6-(hydroxymethyl)-1,2,3,4-tetrahydroisoquinoline
tert-butyl 6-(hydroxymethyl)-3,4-dihydro-1H-isoquinoline-2-carboxylate
tert-butyl 6-(hydroxymethyl)-3,4-dihydroisoquinoline-2(1H)-carboxylate
6-Hydroxymethyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester
2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-6-(hydroxymethyl)-, 1,1-dimethylethyl ester
[Molecular Formula]

C15H21NO3
[MOL File]

622867-52-1.mol
[Molecular Weight]

263.33
Chemical PropertiesBack Directory
[Boiling point ]

403.7±45.0 °C(Predicted)
[density ]

1.153±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[pka]

14.44±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

N-Boc-6-hydroxymethyl-1,2,3,4-tetrahydroisoquinoline is an intermediate used to prepare phosphonate-substituted HIV protease inhibitors for treatment of AIDS and other viral infections. It is also used in the synthesis of immunosuppressant heterocyclic compdounds for treating or preventing diseases assocd. with EDG receptor mediated signal transduction.
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