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633283-39-3

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633283-39-3 Structure

633283-39-3 Structure
IdentificationBack Directory
[Name]

3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
[CAS]

633283-39-3
[Synonyms]

VU 10010
3-Amino-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxylic acid 4-chloro-benzylamide
3-AMINO-N-[(4-CHLOROPHENYL)METHYL]-4,6-DIMETHYLTHIENO[2,3-B]PYRIDINE-2-CARBOXAMIDE
Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-N-[(4-chlorophenyl)methyl]-4,6-dimethyl-
[Molecular Formula]

C17H16ClN3OS
[MDL Number]

MFCD03821022
[MOL File]

633283-39-3.mol
[Molecular Weight]

345.85
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
[solubility ]

Soluble in DMSO > 10 mM
[form ]

Powder
[color ]

White to off-white
Safety DataBack Directory
[Symbol(GHS) ]


GHS06
[Signal word ]

Danger
[Hazard statements ]

H301-H319
[Precautionary statements ]

P264-P270-P280-P301+P310+P330-P305+P351+P338-P337+P313-P405-P501
[Hazard Codes ]

Xn
[Risk Statements ]

22-41
[Safety Statements ]

26-39
Hazard InformationBack Directory
[Uses]

This compound acts as a selective allosteric M4 (Muscarinic Acetylcholine Receptor) agonist.
[Biological Activity]

Selective  allosteric  potentiator  of  M  4 acetylcholine  receptors  (EC  50 values  are  33  and  0.7  nM  for  ACh  in  the  absence  and  presence  of  VU10010 espectively).  Binds  to  an  allosteric  site  on  the  receptor  increasing  affinity  for  ACh  and  coupling  to  G-proteins.
[storage]

Store at -20°C
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